劉培念

男， 中國藥科大學， 教授/研究員/教授級高工或同等級別

學習/工作經(jīng)歷

2024-至今，中國藥科大學，教授，博士生導師
2019，獲國家杰出青年科學基金資助
2015 – 2023，華東理工大學，上海市“東方學者”特聘教授
2016（8-10月），勞倫斯伯克利國家實驗室和加州大學伯克利分校，高級訪問學者
2013 – 2015，香港科技大學物理系和加州大學歐文分校，高級研究學者
2013 – 2023，華東理工大學，化學與分子工程學院精細化工研究所，博士生導師
2012 – 2023，華東理工大學，化學與分子工程學院精細化工研究所，教授
2008 – 2012，華東理工大學，化學與分子工程學院精細化工研究所，副教授
2004 – 2008，香港科技大學化學系和香港理工大學應用生物與化學科技系，博士后
2001 – 2004，蘭州大學，有機化學，博士，導師：涂永強 院士
1998 – 2001，蘭州大學，有機化學，碩士，導師：陳耀祖 院士
1994 – 1998，蘭州大學，有機化學，學士，國家級化學專業(yè)基地班

研究領域和興趣

藥物化學、表面合成化學

主要業(yè)績

主要研究方向是藥物化學和表面合成化學，致力于：1）進行腫瘤靶點相關的小分子藥物設計、合成與活性評價，并基于所設計的新型有機熱釋電材料，開發(fā)出腫瘤的熱釋電動力/免疫協(xié)同療法；2）發(fā)展各種表面合成反應的新策略和新方法，在單分子水平研究有機反應機理，并進一步實現(xiàn)低維有機納米材料的構筑和性質(zhì)研究。截至2024/12，已發(fā)表SCI收錄論文120余篇，從2010年獨立建立課題組至今以通訊作者在Acc. Chem. Res.、 Nat. Commun.（3篇）、J. Am. Chem. Soc.（12篇）、Angew. Chem. Int. Ed.（6篇）、Adv. Mater.、Sci. Adv. 等中科院二區(qū)以上期刊發(fā)表SCI論文80余篇。已主持國家自然科學基金項目8項和省部級項目8項，參與國家自然科學基金重大項目1項和創(chuàng)新研究群體項目1項。

代表成果

1. Y. Wang, W.-W. Gong, Y. Zhao, G.-Y. Xing, L.-X.Kang, F. Sha, Z.-Y. Huang, J.-W. Liu, Y.-J. Han, P. Li, D.-Y. Li,* P.-N. Liu*. Two-DimensionalNonbenzenoid Heteroacene Crystals Synthesized via In-Situ Embedding of LadderBipyrazinylenes on Au(111). Angew. Chem. Int. Ed. 2024,63, e202318142
2. J.-W. Liu, Y. Wang, L.-X. Kang, Y.Zhao, G.-Y. Xing, Z.-Y. Huang, Y.-C. Zhu, D.-Y. Li*, P.-N. Liu*. Two-Dimensional Crystal Transition from Radialene toCumulene on Ag(111) via Retro-[2+1] Cycloaddition. J. Am. Chem. Soc. 2023, 145, 13048.
3. G. Zhu, Y. Jiang, Y. Wang, B.-X.Wang, Y. Zheng, Y. Liu, L.-X. Kang, Z. Li, D. Guan, Y. Li, H.Zheng, C. Liu, J. Jia, T. Lin, P.-N.Liu*, D.-Y. Li*, S. Wang*. Collective Quantum Magnetism inNitrogen-Doped Nanographenes, J. Am. Chem. Soc. 2023. 145, 7136.
4. D.-Y. Li,* Y. Wang, X.-Y. Hou,Y.-T. Ren, L.-X. Kang, F.-H. Xue, Y.-C. Zhu, J.-W. Liu, M. Liu*, X.-Q. Shi*, X.Qiu*, P.-N. Liu*. On-SurfaceSynthesis of [3]Radialenes via [1+1+1] Cycloaddition”. Angew. Chem. Int. Ed. 2022,61, e202117714.
5. D.-Y. Li, X. Qiu, S.-W. Li, Y.-T.Ren, Y.-C. Zhu, C.-H. Shu, X.-Y. Hou, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. Ladder PhenylenesSynthesized on Au(111) Surface via Selective [2+2] Cycloaddition, J. Am. Chem. Soc. 2021, 143, 12955.
6. D.-Y. Li, Y.-C. Zhu, S.-W. Li,C.-H. Shu, P.-N. Liu*. Post-Functionalization of Supramolecular Polymers onSurface and the Chiral Assembly-Induced Enantioselective Reaction, Angew. Chem. Int. Ed. 2021, 60, 11370.
7. C.-H. Shu, Y. He, R.-X. Zhang,J.-L. Chen, A. Wang, P.-N. Liu*.Atomic-Scale Visualization of Stepwise Growth Mechanism of Metal-Alkynyl Networkson Surfaces, J. Am. Chem. Soc. 2020, 142, 39, 16579.
8. D.-Y. Li, S.-W. Li,Y.-L. Xie, X. Hua, Y.-T. Long, A. Wang, P.-N. Liu*. On-surface synthesis ofplanar dendrimers via divergent cross-coupling reaction, Nat. Commun., 2019, 10, 2414.
9. X. Li, X. Ma, Z. Wang, P.-N.Liu*, L. Zhang*. Bifunctional Phosphine Ligand Enabled Gold‐CatalyzedAlkynamide Cycloisomerization: Access to Electron‐Rich 2‐Aminofurans and TheirDiels–Alder Adducts, Angew. Chem. Int.Ed., 2019, 58, 17180.
10. C.-H.Shu, M.-X. Liu, Z.-Q. Zha, J.-L. Pan,S.-Z. Zhang, Y.-L. Xie, J.-L.Chen, D.-W. Yuan, X.-H. Qiu*, P.-N. Liu*. On-surface synthesis ofpoly(p-phenylene ethynylene) molecular wires via in situ formation ofcarbon-carbon triple bond, Nat. Commun.,2018, 9, 2322.
11. G. Kuang?, S.-Z. Chen?, L.Yan, K.-Q. Chen*, X. Shang, P.-N. Liu*,N. Lin*. Negative Differential Conductance in Polyporphyrin Oligomers withNonlinear Backbones, J. Am. Chem. Soc., 2018, 140, 570.
12. L. Yan,* B.Xia, Q. Zhang, G. Kuang, H. Xu, J. Liu, P.-N. Liu*, N. Lin*. Stabilizing andOrganizing Bi3Cu4 and Bi7Cu12 Nanoclusters in Two-Dimensional Metal-OrganicNetworks, Angew. Chem. Int. Ed., 2018,57, 4617.
13. D.-Y. Li, H.-J. Chen, P.-N.Liu*. Tunable Cascade Reactions of Alkynols with Alkynes under CombinedSc(OTf)3 and Rhodium Catalysis, Angew.Chem. Int. Ed., 2016, 55, 373.
14. G. Kuang, S.-Z. Chen, W. Wang, T. Lin, K. Chen, X. Shang, P.-N. Liu,* N. Lin*. Resonant Charge Transport in Conjugated Molecular Wiresbeyond 10 nm Range, J. Am. Chem. Soc.,2016, 138, 11140.
15. L. Dong, P.-N. Liu*,N. Lin*. Surface-Activated Coupling Reactions Confined on a Surface, Acc. Chem. Res., 2015, 48, 2765.
16. T. Lin, X.-S. Shang, J. Adisoejoso, P.-N. Liu*, N. Lin*. Steering On-Surface Polymerization withMetal-Directed Template, J. Am. Chem.Soc., 2013, 135, 3576.
17. J. Adisoejoso, Y. Li, J. Liu, P.-N. Liu*, N. Lin*. Two-Dimensional Metallo-SupramolecularPolymerization: Towards Size Controlled Multi-strand Polymers, J. Am. Chem. Soc., 2012, 134, 18526.
18. J. Liu, T. Lin, Z. Shi, F. Xia, P.-N. Liu*, N. Lin*. Structural Transformation of Two-DimensionalMetal-Organic Coordination Networks Driven by Intrinsic In-Plane Compression, J. Am. Chem. Soc., 2011, 133, 18760.
19. Z. Shi, J. Liu, T. Lin, F. Xia, P.-N. Liu*, N. Lin*. Thermodynamics and Selectivity ofTwo-dimensional Metallo-Supramolecular Self-assembly Resolved at MolecularScale, J. Am. Chem. Soc., 2011, 133, 6150.
20. W. Wang, S. Wang, X. Li, J.-P.Collin, J. Liu, P.-N. Liu*, N. Lin*.Probing Electronic Superexchange Coupling at Isolated Poly-p-phenyleneMolecules, J. Am. Chem. Soc., 2010, 132, 8774.

*以上信息由高級會員個人更新和維護。