張文科

男， 吉林大學(xué)超分子結(jié)構(gòu)與材料國(guó)家重點(diǎn)實(shí)驗(yàn)室， 教授/研究員/教授級(jí)高工或同等級(jí)別

學(xué)習(xí)/工作經(jīng)歷

1993.09-1997.07，吉林大學(xué)化學(xué)系，本科生
1997.09-2002.07，吉林大學(xué)化學(xué)學(xué)院，研究生（碩博連讀）
2001.04-2002.03，德國(guó)慕尼黑大學(xué)應(yīng)用物理系，博士生聯(lián)合培養(yǎng)
2003.03-2004.09，英國(guó)諾丁漢大學(xué)藥學(xué)院，博士后
2004.10-2007.05，英國(guó)諾丁漢大學(xué)化學(xué)學(xué)院，博士后
2007.06-至今，吉林大學(xué)超分子結(jié)構(gòu)與材料國(guó)家重點(diǎn)實(shí)驗(yàn)室，教授

研究領(lǐng)域和興趣

聚合物單分子力譜與超分子相互作用，高分子結(jié)晶與熔融，生物大分子相互作用，高分子力化學(xué)

主要業(yè)績(jī)

長(zhǎng)期從事聚合物單分子力譜研究，近年來(lái)在高分子凝聚態(tài)體系的分子間相互作用及超分子組裝推動(dòng)力研究方面取得一系列重要的創(chuàng)新性成果，部分成果發(fā)表在Nat. Commun.，J. Am. Chem. Soc. 等重要國(guó)際期刊上，并受到國(guó)際同行的廣泛關(guān)注與積極評(píng)價(jià)。應(yīng)邀在國(guó)際國(guó)內(nèi)重要學(xué)術(shù)會(huì)議做邀請(qǐng)報(bào)告30余次（其中包括3次大會(huì)報(bào)告）。2015年獲得國(guó)家杰出青年科學(xué)基金獲資助，2017年入選科技部“創(chuàng)新人才推進(jìn)計(jì)劃”中青年科技創(chuàng)新領(lǐng)軍人才，2018年入選中組部“萬(wàn)人計(jì)劃”領(lǐng)軍人才。主持國(guó)家重大科研儀器研制項(xiàng)目（自由申請(qǐng)）及基金委面上等項(xiàng)目。擔(dān)任中國(guó)化學(xué)會(huì)高分子學(xué)科委員會(huì)、生物物理化學(xué)專業(yè)委員會(huì)、超分子化學(xué)專業(yè)委員會(huì)委員，AIMS Biophysics及Langmuir期刊編委。

代表成果

[1] Y. Song, Z. Ma, W. K. Zhang*, Manipulation of a single polymer chain: from the nanomechanical properties to dynamic structure evolution, Macromolecules, 2022, 55, 4177?4199. DOI: 10.1021/acs.macromol.2c00076; (Invited Perspective, ACS Editors’ Choice)
[2] X. N. Zhang, X. Kou, W. Zhang, W. K. Zhang*, Identification of the new type of G-Quadruplex with multiple vacant sites in human telomeric DNA, CCS Chem., 2022, 4, 3023–3035.
[3] R. Yao, X. Li, N. Xiao, W. Weng*, W. K. Zhang*, Single-molecule observation of mechanical isomerization of spirothiopyran and subsequent Click addition, Nano Res., 2021, 14(8): 2654–2658. DOI:10.1007/s12274-020-3268-9;
[4] X. N. Zhang, Y. Q. Zhang and W. K. Zhang*, Dynamic topology of double-stranded telomeric DNA studied by single-molecule manipulation in vitro, Nucleic Acids Res., 2020, 48, 6458–6470. DOI: 10.1093/nar/gkaa479;
[5] Z. W. Ma, P. Yang, X. Y. Zhang, K. Jiang, Y. Song*, W. K. Zhang*, Quantifying the chain folding in polymer single crystals by single-molecule force spectroscopy, ACS Macro Lett., 2019, 8, 1194?1199. DOI: 10.1021/acsmacrolett.9b00607; (ACS Editors’ Choice)
[6] P. Yang, Y. Song, W. Feng, W. K. Zhang*, Unfolding of a single polymer chain from the single crystal by air-phase single-molecule force spectroscopy: toward better force precision and more accurate description of molecular behaviors, Macromolecules, 2018, 51, 7052?7060. DOI: 10.1021/acs.macromol.8b01544;
[7] H. Zhang, X. Li, Y. J. Lin, F. Gao, Z. Tang, P. F. Su, W. K. Zhang*, Y. Z. Xu, W. G. Weng*, R. Boulatov*, Multi-modal mechanophores based on cinnamate dimers, Nat. Commun., 2017, 8, 1147. DOI: 10.1038/s41467-017-01412-8;
[8] Y. R. Xue, X. Li, H. B. Li, W. K. Zhang*, Quantifying thiol-gold interactions towards the efficient strength control, Nat. Commun., 2014, 5:4348. DOI: 10.1038/ncomms5348; (Highly Cited Paper)
[9] N. N. Liu, B. Peng, Y. Lin, Z. H. Su, Z. W. Niu, Q. Wang, W. K. Zhang*, H. B. Li, J. C. Shen, Pulling genetic RNA out of tobacco mosaic virus using single-molecule force spectroscopy, J. Am. Chem. Soc., 2010, 132, 11036-11038. DOI:10.1021/ja1052544;
[10] K. Liu, Y. Song, W. Feng, N. N. Liu, W. K. Zhang*, X. Zhang, Extracting a single polyethylene oxide chain from a single crystal by a combination of atomic force microscopy imaging and single-molecule force spectroscopy: toward the investigation of molecular interactions in their condensed states, J. Am. Chem. Soc., 2011, 133, 3226-3229. DOI: 10.1021/ja108022h. (Highlighted by Nature Materials)

*以上信息由高級(jí)會(huì)員個(gè)人更新和維護(hù)。