樂學義

男， 華南農業(yè)大學， 教授/研究員/教授級高工或同等級別

學習/工作經歷

1978.09-1982.07, 湖北師范大學(原黃石師范學院）化學系,本科生
1982.08-1985.08, 湖北省應城市教師進修學校,教師
1985.09-1988.06, 華中師范大學化學系,碩士研究生
1988.06-1993.08, 湖北工程學院（原孝感師范?？茖W校）化學系,講師
1993.09-1996.06, 中山大學化學化工學院,博士研究生
1997.12-2001.12, 華南農業(yè)大學理學院，副教授、碩士生導師(1999.06-)，期間擔任應用化學系副主任(2001.03-2001.04) 、理學院副院長兼任應用化學系主任（2001.05- 2006.12）
2001.12-2014.12，華南農業(yè)大學理學院,教授(破格) 、博士生導師(2005/06-)，期間擔任理學院院長（2007/01-2014/12）
2015.01-現(xiàn)在, 華南農業(yè)大學材料與能源學院應用化學系,教授,博(碩)士生導師

研究領域和興趣

生物無機化學

主要業(yè)績

長期從事生物無機化學、藥物化學、食品科學等交叉學科研究,先后承擔省部級以上科研項目20余項,已公開發(fā)表學術論文180多篇,其中90余篇被SCI收錄,獲得國家發(fā)明專利2項,作為主要參加人獲廣東省自然科學一等獎1項,合作出版編著1本。

代表成果

1. Dai-Hong Cai, Chun-Lian Zhang, Qi-Yan Liu, Liang He, Yun-Jun Liu, Ya-Hong Xiong, Xue-Yi Le*. Synthesis, DNA binding, antibacterial and anticancer properties of two novel water-soluble copper(II)
complexes containing gluconate. European Journal of Medicinal Chemistry,213( 2021), doi.org/ 10.1016/ j.ejmech. 2021.113182
2. Yong-Yu Qi, Qian Gan , Ya-Xian Liu, Ya-Hong Xiong, Zong-Wan Mao, Xue-Yi Le*. Two new Cu(II) dipeptide complexes based on 5-methyl-2-(2’-pyridyl)benzimidazole as potential antimicrobial and anticancer drugs:Special exploration of their possible anticancer mechanism. European Journal of Medicinal Chemistry, 154(2018), DOI: 10.1016/j.ejmech.2018.05.023;
3．Chun-Lian Zhang, Ya-Xian Liu, Xue-Mei Zhang, Shi Chen, Fang Shen, Ya-Hong Xiong, Wei Liu,, Zong-Wan Mao, Xue-Yi Le*. Synthesis, characterization, DNA/HSA interactions and in vitro cytotoxic activities of two novel water-soluble copper(II) complexes with 1,3,5-triazine derivative ligand and amino acids. Materials Science & Engineering C, 91(2018), DOI: 10.1016/j.msec.2018.05.065;
4.Yujia Liu, Yanxue Cai, Danyang Ying, Yinlian Fu, Yahong Xiong, Xueyi Le*. Ovalbumin as a carrier to significantly enhance the aqueous solubility and photostability of curcumin: Interaction and binding mechanism study. International Journal of Biological Macromolecules, 116(2018), DOI: 10.1016/j.ijbiomac.2018.05.089;
5. Xia-Bing Fu, Dan-Dan Liu, Yuan Lin, Wei Hu, Zong-Wan Mao and Xue-Yi Le*. Water-soluble DNA minor groove binders as potential chemotherapeutic agents: synthesis, characterization, DNA binding and cleavage, antioxidation, cytotoxicity and HSA interactions. Dalton Transaction, 43(2014), DOI: 10.1039/c3dt53577k;

*以上信息由高級會員個人更新和維護。