燕云峰

男， 浙江工業(yè)大學生物工程學院， 教授/研究員/教授級高工或同等級別

學習/工作經歷

2017.03-至今， 浙江工業(yè)大學生物工程學院，教授
20120.8-2017.01，University of Texas Southwestern Medical Center, Research Scientist
2011.03-2012.07， University of Massachusetts Amherst, Postdoc
2009.10-2011.02，上海師范大學化學系，講師
2007.07-2009.09，復旦大學高分子科學系，博士后
2002.09-2007.06，中國科學技術大學化學物理系，博士
1998.09-2002.06，安徽師范大學化學系，本科

研究領域和興趣

高分子化學、生物材料、基因治療和生物醫(yī)學

主要業(yè)績

研究工作聚焦生物材料和納米生物藥物領域。主持國家自然科學基金聯(lián)合基金、面上項目和浙江省自然科學基金重點項目等多項。在PNAS, Biomaterials等知名期刊發(fā)表論文六十余篇，授權中國發(fā)明專利4項。擔任中國感光學會生物基功能大分子材料與技術專業(yè)委員會委員，長期擔任Nat. Commun., J. Mater. Chem. B, Chem. Commun., Acs Appl. Mater. Inter. Sci., Acta Biomater.等主流期刊審稿人。

代表成果

1. Yichen Li, Yi Cao, Hao Bai, Luwei Zhang, Baiqiu Chen, Chengfan Wu, Qi Shuai, and Yunfeng Yan* Incorporation of disulfide bonds into ionizable lipids enables efficient splenic mRNA delivery and potent immunotherapy in mice. Chemical Engineering Journal 2025, 516, 164285
2. Yuduo Gao, Luwei Zhang, Ziyue Wang, Hao Bai, Chengfan Wu, Qi Shuai, and Yunfeng Yan* Enhanced Pulmonary and Splenic mRNA Delivery Using DOTAP-Incorporated Poly(beta-Amino Ester)-Lipid Nanoparticles. Biomacromolecules 2025, 26(1), 623-634
3. Pingge Jiang, Yaxuan Wang, Qiong Wu, Ziyue Wang, Chengfan Wu, Qi Shuai, and Yunfeng Yan* Development of diselenide-containing poly(β-amino ester)s for potent mRNA delivery to the spleen. Biomacromolecules 2025, accepted
4. Chengfan Wu, Pingge Jiang, Wen Su, and Yunfeng Yan* Alkaline Phosphatase-Instructed Peptide Assemblies for Imaging and Therapeutic Applications. Biomacromolecules 2024, 25(9), 5609–5629
5. Qi Shuai, Wanxuan Xie, Siyuan Chen, Huahui Su and Yunfeng Yan* Novel aromatic moieties-modified poly(glycidyl amine)s with potent siRNA delivery and cancer treatment effect. Journal of Materials Chemistry B 2024, 12, 3115
6. Wenfei Qian, Hao Bai, Yunfeng Yan*, and Qing Bi Regulation of Physicochemical Properties of Alginate-based Hydrogels and Preliminary Applications in Wound Healing. International Journal of Biological Macromolecules 2024, 283, 137627
7. Yunfeng Yan,* Xiaomin Liu, Longyu Wang, Chengfan Wu, Qi Shuai, Yanmei Zhang, and Shuai Liu Branched Hydrophobic Tails in Lipid Nanoparticles Enhance mRNA Delivery for Cancer Immunotherapy. Biomaterials 2023, 301, 122279
8. Wenbo Ye, Fangtao Zhu, Yue Cai, Longyu Wang, Guangliang Zhang, Guangkuo Zhao, Xiaohe Chu, Qi Shuai, Yunfeng Yan* Improved paclitaxel delivery with PEG-b-PLA/zein nanoparticles prepared via flash nanoprecipitation. International Journal of Biological Macromolecules 2022, 221, 486-495
9. Qi Shuai, Fangtao Zhu, Mengdan Zhao, YunfengYan* mRNA delivery via non-viral carriers for biomedical applications. International Journal of Pharmaceutics 2021, 607, 121020
10. Yunfeng Yan, Li Liu, Hu Xiong, Jason B. Miller, Kejin Zhou, Petra Kos, Kenneth E. Huffman, Sussana Elkassih, John W. Norman, Ryan Carstens, James Kim, John D. Minna, and Daniel J. Siegwart* Functional Polyesters Enable Selective siRNA Delivery to Lung Cancer over Matched Normal Cells. Proceedings of the National Academy of Sciences of the United States of America 2016, 113, E5702-E5710

*以上信息由高級會員個人更新和維護。